The Oncology Precision Therapeutics and Imaging Core (OPTIC) at the Herbert Irving Comprehensive Cancer Center is a a core facility for patient-derived cancer models and pre-clinical services to support the precision cancer medicine initiative at Columbia University. Our goal is to improve the significance and predictability of translational research by facilitating the discovery and pre-clinical validation of personalized cancer treatments.
Individualizing treatment for patients is the future of cancer research. We develop tumor models using patient derived xenografts (PDX), which provide us with a non-invasive method to monitor tumor progression and drug efficacy for patient-specific tumor samples. OPTIC also works in partnership with the Small Animal Imaging Shared Resource (SAISR) here at Columbia University to provide state-of-the-art magnetic resonance imaging and spectroscopy studies for quantitative image analysis.